2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine - Names and Identifiers
Name | 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine
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Synonyms | BlonserinImpurity14 Blonanserin Impurity 14 Blonanserin Intermediate 2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10... 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[... 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocyclooctapyridine 2-chloro-4-(4-fluorophenyl)5,6,7,8,9,10-hexahydrocycloocta[b]pyridine 2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine Cycloocta[b]pyridine, 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-
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CAS | 132813-14-0
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EINECS | 1592732-453-0 |
InChI | InChI=1/C17H17ClFN/c18-17-11-15(12-7-9-13(19)10-8-12)14-5-3-1-2-4-6-16(14)20-17/h7-11H,1-6H2 |
2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine - Physico-chemical Properties
Molecular Formula | C17H17ClFN
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Molar Mass | 289.77 |
Density | 1.175 |
Melting Point | 137-140°C |
Boling Point | 414.7±45.0 °C(Predicted) |
Flash Point | 204.6°C |
Solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
Vapor Presure | 1.05E-06mmHg at 25°C |
Appearance | Solid |
Color | Off-White |
pKa | 1.49±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Irritant |
Refractive Index | 1.561 |
MDL | MFCD09955376 |
2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine - Introduction
2-Chloro-4-(4-fluorophenyl)-5,6,7,8, 9,10-hexahydrocyclooctane [B] pyridine is an organic compound with a chemical formula of C18H22ClFN and a structural unit containing a six-membered ring and a pyridine ring.
Nature:
-Appearance: White crystalline solid
-Melting point: approximately 50-52 degrees Celsius
-Solubility: Good solubility in non-polar organic solvents
Use:
-2-Chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocyclooctane [B] pyridine can be used as a pharmaceutical intermediate for the synthesis of some drugs.
-It can also be used as a catalyst in organic synthesis.
Preparation Method:
-A commonly used synthesis method is the reaction of 2-bromo-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocyclooctane [B] pyridine with sodium nitrite.
Safety Information:
-Since 2-chloro-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocyclooctane [B] pyridine is an organic compound, it should be used Pay attention to comply with laboratory safety procedures.
-This compound may be toxic and irritating, and contact with skin and eyes may cause irritation and inflammation. When in use, wear appropriate personal protective equipment such as gloves and goggles.
-Further research and use of this compound may require more detailed safety information and protective measures.
Last Update:2024-04-09 21:04:16